Resampling is changing the amount of image data as you change either the pixel dimensions or the resolution of an image. When you downsample (decrease the number of pixels), information is deleted from the image. When you resample up (increase the number of pixels, or upsample), new pixels are added. You specify an interpolation method to determine how pixels are added or deleted.

Keep in mind that resampling can result in poorer image quality. For example, when you resample an image to larger pixel dimensions, the image loses some detail and sharpness. Applying the Unsharp Mask filter to a resampled image can help refocus the image details.
You can avoid the need for resampling by scanning or creating the image at a sufficiently high resolution. If you want to preview the effects of changing pixel dimensions on‑screen or to print proofs at different resolutions, resample a duplicate of your file.
Photoshop resamples images using an interpolation method to assign color values to any new pixels based on the color values of existing pixels. You can choose which method to use in the Image Size dialog box.
You can specify a default interpolation method
to use whenever Photoshop resamples image data. Choose Edit >
Preferences > General (Windows) or Photoshop >
Preferences > General (Mac OS), and then choose
a method from the Image Interpolation Methods menu.
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