Eyedropper tool

Any painting tool + Alt or any shape tool + Alt (except when Paths option is selected)

Any painting tool + Option or any shape tool + Option (except when Paths option is selected)

Select background color

Eyedropper tool + Alt-click

Eyedropper tool + Option-click

Color sampler tool

Eyedropper tool + Shift

Eyedropper tool + Shift

Deletes color sampler

Color sampler tool + Alt-click

Color sampler tool + Option-click

Sets opacity, tolerance, strength, or exposure for painting mode

Any painting or editing tool + number keys (e.g., 0 = 100%, 1 = 10%, 4 then 5 in quick succession = 45%) (When airbrush option is enabled, use Shift + number keys)

Any painting or editing tool + number keys (e.g., 0 = 100%, 1 = 10%, 4 then 5 in quick succession = 45%) (When airbrush option is enabled, use Shift + number keys)

Sets flow for painting mode

Any painting or editing tool + Shift + number keys (e.g., 0 = 100%, 1 = 10%, 4 then 5 in quick succession = 45%) (When airbrush option is enabled, omit Shift)

Any painting or editing tool + Shift + number keys (e.g., 0 = 100%, 1 = 10%, 4 then 5 in quick succession = 45%) (When airbrush option is enabled, omit Shift)

Cycles through blending modes

Shift + + (plus) or – (minus)

Shift + + (plus) or – (minus)

Fills selection/layer with foreground or background color

Alt + Backspace, or Control + Backspace^†

Option + Delete, or Command + Delete^†

Fills from history

Control + Alt + Backspace^†

Command + Option + Delete^†

Displays Fill dialog box

Shift + Backspace

Shift + Delete

Lock transparent pixels on/off

/ (forward slash)

/ (forward slash)

Connects points with a straight line

Any painting tool + Shift-click

Any painting tool + Shift-click

^†Hold down Shift to preserve transparency