After you’ve applied effects to a layer, you can temporarily disable one or all the effects on the layer to concentrate on another aspect of your composition. Effects that are disabled do not appear in the Composition panel and typically are not included when the layer is previewed or rendered. However, in the Render Queue panel, you can specify that the composition is rendered for final output with all effects on, regardless of which effects are rendered for previews in the Composition panel. Disabling an effect does not delete the keyframes created for any of the effect properties; all keyframes remain until the effect is deleted from the layer.

You can’t disable an animation preset or delete it from a layer as a unit. You can, of course, individually delete or disable the effects, keyframes, and expressions that it comprises.